Recent evidence suggests that the hippocampus
may integrate overlapping memories into relational
representations, or schemas, that link indirectly
related events and support flexible memory expression.
Here we explored the nature of hippocampal
neural population representations for multiple features
of events and the locations and contexts in
which they occurred. Hippocampal networks developed
hierarchical organizations of associated elements
of related but separately acquired memories
within a context, and distinct organizations for
memories where the contexts differentiated objectreward
associations. These findings reveal neural
mechanisms for the development and organization
of relational representations.
Sam McKenzie, Andrea J. Frank, Nathaniel R. Kinsky, Blake Porter, Pamela D. Riverère, and Howard Eichenbaum. Hippocampal Representation of Related and Opposing Memories Develop within Distinct, Hierarchically Organized Neural Schemas. Neuron. 2 July 2014. 83(1)202 – 215. http://dx.doi.org/10.1016/j.neuron.2014.05.019
Leave a Reply